The Democratic Republic of Congo (DRC) is currently facing the largest outbreak of the viral mpox disease ever documented, with tens of thousands infected as of June. Previously known as monkeypox, the mpox disease, caused by the monkeypox virus, typically spreads from animals to humans. Endemic to Central and West Africa's forested regions, the virus is related to the smallpox virus and can be fatal in severe cases, manifesting with symptoms like a fever and an itchy rash. This outbreak started in May 2022 in the Kwango province and has now spread to 22 out of 26 provinces in the DRC, including the capital, Kinshasa, with a new strain discovered in Kamituga. The total reported cases surpassed 21,000 with over 1,000 deaths. Two variants of mpox exist - Clade 2 is less deadly and was spread in a 2022 outbreak affecting multiple countries, while Clade 1, more severe, is causing the current DRC outbreak, potentially spreading through sexual contact. The disease's transmission through sexual contact, particularly among high-risk groups, poses new challenges for controlling the virus, as the symptoms are presenting differently this time. Authorities in the DRC are facing obstacles due to limited testing facilities, inadequate resources, and a scarcity of vaccines. The lack of public awareness contributes to difficulties in self-reporting and containment. The risk of transmission to neighbouring countries heightens the regional and global concern. Despite containment efforts, the virus has already spread to neighbouring Congo and Cameroon, signifying a potential regional epidemic. Vigilance across Africa is crucial to prevent further spread of the disease.